Paul C. Simpson

This study shows chronic treatment with a 1A-adrenergic agonist improves mitochondrial function and reverses right ventricular failure in a mouse model.

This study shows that Ca2+ increases cardiac muscle viscoelasticity independently of active force development, with a >6-fold increase in apparent viscoelasticity at higher Ca2+ levels.

This study shows that norepinephrine modulates synapses via astrocytic adrenergic receptors and Ca2+ dynamics, independent of neuronal receptors.

The paper shows that cortical astrocytes mediate learned behavior by extending norepinephrine signals through calcium dynamics and ATP release, influencing neuronal encoding of task variables.