Kathrin Sauter

A bistable inhibitory OptoGPCR for multiplexed optogenetic control of neural circuits

This paper identifies PdCO as a bistable GPCR with high temporal precision for optogenetic control of neural circuits in vivo.

Optimized design and in vivo application of optogenetically functionalized Drosophila dopamine receptors

This paper optimizes optogenetically functionalized GPCRs to achieve specific in vivo neuromodulatory signaling in Drosophila, showing rescue of endogenous receptor function.

Temporally extended and reversible neuronal silencing with Aion

The paper introduces Aion, a bistable anion-conducting channelrhodopsin with a long open state and precise light-switchable control, enabling extended neuronal silencing in Drosophila.

A comparison of viral strategies and model systems to target norepinephrine neurons in the locus coeruleus reveals high variability in transgene expression patterns

The paper compares viral strategies for targeting locus coeruleus norepinephrine neurons, finding variability in transgene expression and no behavioral differences in cre-expressing mice.

BiPOLES: a tool for bidirectional dual-color optogenetic control of neurons

BiPOLES is an optogenetic tool that allows bidirectional control of neuronal activity using two different light colors, enabling both excitation and inhibition of the same neurons in a single experiment.

Optogenetic silencing of neurotransmitter release with a naturally occurring invertebrate rhodopsin

This paper introduces eOPN3, a modified mosquito rhodopsin that suppresses synaptic transmission with high spatiotemporal precision in vivo.

Discrete escape responses are generated by neuropeptide-mediated circuit logic

The paper identifies a somatosensory network in Drosophila larvae that uses neuropeptide action to gate specific escape behaviors based on sensory input type.