Gavin P. Kelly

This study reanalyzes image datasets to emphasize robust experimental design and effect sizes over statistical significance, providing open-access code to improve reproducibility.

The paper investigates how CDKN2A and other 9p21 gene losses influence oesophageal cancer progression, finding context-dependent effects on survival and immune infiltration.

The paper identifies regulatory T cells as mediators of resistance to KRAS-G12C inhibitors and anti-PD-1 therapy through spatial proteomic analysis of lung cancer models.

This study generates fam83f knock-out zebrafish to investigate Fam83f's role in hatching and DNA damage response, finding impaired autophagy and increased radiation sensitivity.

The paper shows that growth deceleration during development is linked to hypoxia, with HIF-1 regulating TOR signaling to prevent oxygen demand from exceeding supply.

This study identifies ARID3A as a regulator of intestinal epithelial cell proliferation and differentiation, showing its role in maintaining tissue homeostasis through modulation of TA cell dynamics.

The paper identifies altered nucleocytoplasmic partitioning and nuclear accumulation of polyadenylated transcripts as conserved features of quiescence in neural stem cells.