Walter Rossmanith

This study shows that tRNA thiolation defects in humans cause proteostasis and tissue homeostasis issues, but mice with similar defects develop normally.

The paper introduces a differential model m6ADyn to predict m6A dynamics by integrating mRNA metabolism and validates its predictions through experimental confirmation.

The paper shows that m1A methylation of ND5 mRNA, catalyzed by TRMT10C, leads to translation repression and mitochondrial dysfunction in Alzheimer's disease.

This study shows that human YBEY is essential for mitochondrial ribosome biogenesis, leading to respiratory deficiency and mitochondrial abnormalities.

This paper introduces MASTER-seq, a method to quantitatively profile m6A sites at single-nucleotide resolution, revealing a predictable code that determines m6A stoichiometry and dynamics.

The paper identifies a homozygous variant in KIAA0391 (PRORP) as a cause of Perrault syndrome, showing reduced mitochondrial RNase P activity and impaired tRNA processing.