Nima Abedpour

Combination of enhanced gene activation and cell death causes lethal inflammatory pulmonary fibrosis

The paper shows that enhanced gene activation in specific LUBAC mutants leads to cell death and lethal lung fibrosis, revealing gene activation as a root cause of inflammatory disease.

Single recipient cell tracking of tellurium-labeled extracellular vesicle proteomes (TeLEV) identifies EV-driven immunomodulation

The paper introduces TeLEV, a method to track EV proteomes in immune cells, revealing EV-driven immunomodulation through STAT5-dependent mechanisms.

T-cell development and activation in humanized mice lacking mouse major histocompatibility complexes

This study shows human T-cell development in humanized mice can occur without mouse MHCs and is enhanced by lentiviral delivery of HLA and cytokines.

Predicting gene expression level in E. coli from mRNA sequence information

The paper develops PGExpress, a tool to predict translation efficiency in E. coli using mRNA sequence features, achieving 74% accuracy and 0.81 AUC.