Sonia Santana‐Varela

Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes

The paper identifies analgesic targets in mouse sensory neurons by analyzing translatomes in somata and terminals under different pain conditions.

Molecular basis of FAAH-OUT-associated human pain insensitivity

The paper identifies how the FAAH-OUT lncRNA regulates FAAH expression through DNA methylation and enhancer activity, linking it to pain insensitivity.

Sensitization of cutaneous primary afferents in bone cancer revealed by in vivo calcium imaging

The paper investigates changes in bone-innervating afferents in cancer-induced bone pain using calcium imaging and retrograde labeling, finding altered excitability in cutaneous afferents but not bone marrow afferents.

Sensory neuron-derived Nav1.7 contributes to dorsal horn neuron excitability

This study shows that Nav1.7 from sensory neurons affects dorsal horn neuron excitability, with functional effects not predicted by mRNA levels.

Brain-derived neurotrophic factor derived from peripheral sensory neurons plays a critical role in pain chronification

This study shows that BDNF from peripheral sensory neurons is critical for transitioning acute to chronic pain.

Regulation of somatosensory mechanotransduction by Annexin A6

This study identifies Annexin A6 as a modulator of somatosensory mechanotransduction by affecting mechanically-activated currents in sensory neurons.