Magdalena Dziembowska

Temporal and protein-specific S-palmitoylation supports synaptic and neural network plasticity

This study shows that S-palmitoylation differentially affects synaptic plasticity and neuronal spiking timing, targeting specific proteins in excitatory synapses.

Polyadenylation landscape of in vivo long-term potentiation in the rat brain

This study uses nanopore sequencing to analyze polyadenylation changes in rat hippocampi during long-term potentiation, revealing dynamic shifts in poly(A) tail length and composition.

Delayed development of inner hair cell ribbon synapses in a mouse model of fragile X syndrome

The paper examines delayed maturation of inner hair cell ribbon synapses in Fmr1 KO mice, linking it to auditory circuit development issues.

Terminal nucleotidyltransferase Tent2 microRNA tailing regulates excitatory/inhibitory balance in the hippocampus

This study shows that TENT2-dependent microRNA tailing affects synaptic transmission and excitatory/inhibitory balance in the hippocampus of mice.

Mutation in mitochondrial chaperone TRAP1 results in male-specific autism

A mutation in the TRAP1 gene causes autism-like behaviors in male mice, suggesting a role for mitochondrial protein homeostasis in male-specific autism.

Mitochondria biogenesis in the synapse is supported by local translation

The paper shows that mitochondrial proteins are locally synthesized at synapses and incorporated into respiratory chain complexes, supporting local mitochondrial biogenesis.