Author

Abdirahman Hayir

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Eric D. QueathemiD· 3 shared Kyle FulghumiD· 3 shared Patrycja PuchalskaiD· 3 shared Peter A. CrawfordiD· 3 shared Alisa B. NelsoniD· 2 shared Curtis C. HugheyiD· 2 shared D. André d’Avignon· 2 shared David B. StaggiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

Eric D. QueathemORCID

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Author profile →

3 papers

Recent·Most cited

Diet-Dependent Cognitive Benefits of Exogenous Ketone Body Precursor, (R,S)-1,3,-Butanediol, in a Mouse Model of Tauopathy

Kyle Fulghum, Abdirahman Hayir, RUUSU ANKERIASNIEMI, Cynthia Shaddy‐Gouvion, Cha Mee Vang, Sebastian F. Salathe, Eric D. Queathem, Curtis C. Hughey, Mohammad Haeri, John P. Thyfault, Patrycja Puchalska, Peter A. Crawford

This study shows that (R,S)-1,3-butanediol improves memory in female tauopathy mice on chow but not on high-fat diets or after long-term use, highlighting sex and diet-dependent cognitive benefits.

bioRxiv · Jun 8, 2026 · PreprintAnimal Behavior & Cognition

Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate

Eric D. Queathem, David B. Stagg, Alisa B. Nelson, Alec Chaves, Scott B. Crown, Kyle Fulghum, D. André d’Avignon, Justin R. Ryder, Patrick J. Bolan, Abdirahman Hayir, Jacob R. Gillingham, Shannon Jannatpour, Ferrol I. Rome, Ashley S. Williams, Deborah M. Muoio, , Peter A. Crawford

Journal of Clinical Investigation · Apr 24, 2025Peer-reviewedBiochemistry

Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation

Eric D. Queathem, Zahra Moazzami, David B. Stagg, Alisa B. Nelson, Kyle Fulghum, Abdirahman Hayir, Alisha Seay, Jacob R. Gillingham, D. André d’Avignon, Xianlin Han, Hai‐Bin Ruan, Peter A. Crawford, Patrycja Puchalska

The paper shows ketogenesis supports PUFA homeostasis in hepatocytes by enabling FA elongation, and its disruption leads to lipid imbalances similar to MASLD.

Science Advances · Jan 29, 2025Peer-reviewedBiochemistry