Author

Helen E. Bryant

University of SheffieldORCID 0000-0003-2720-7020Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Agnieszka GambusiD· 1 shared Aidan J. DohertyiD· 1 shared Akhil BowryiD· 1 shared Alexandra K. Walker· 1 shared Alice L. B. PyneiD· 1 shared Ann Liza Piberger· 1 shared Daniel González‐AcostaiD· 1 shared Dušan RačkoiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Agnieszka GambusORCID

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedJul 1, 2025

Under or Over? Tracing Complex DNA Structures with High-Resolution Atomic Force Microscopy

Elizabeth P. Holmes, Max C. Gamill, James Iain Provan…·Alice L. B. Pyne

This paper introduces a high-throughput AFM-based pipeline using deep learning to trace DNA topology, revealing new insights into DNA structures and their interactions.

21 citationstop 2%

XenopusE. coli

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedNov 17, 2020

PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts

Ann Liza Piberger, Akhil Bowry, Richard D. Kelly…·Eva Petermann

This study shows that PrimPol creates single-stranded gaps at bulky DNA adducts, which recruit RAD51 for homologous recombination, facilitating DNA repair in mammalian cells.

118 citationstop 3%

humanDNA methylation

𝕏 PostBluesky