Noa Katz

This paper introduces an IFFL-based CRISPR-Cas system to reduce gene expression variability, demonstrating improved dosage control for RAI1 in a mouse model.

The paper describes a cell-free assay using fluorescent particles and labeled hACE2 to screen inhibitors of SARS-CoV-2 Spike-hACE2 binding, demonstrating its effectiveness with known inhibitors and RNA-based trapping.

The paper uses high-throughput oligo libraries and machine learning to design non-repetitive RNA binding cassettes for gene editing and RNA tracking, demonstrating their functionality in mammalian cells.

The paper shows that synthetic 5 UTRs can be up- or down-regulated by RBP binding, revealing RNA-RBP interactions that control translation.

The paper develops an in vivo method to quantify RNA-binding protein-RNA interactions using a reporter gene repression assay and SHAPE-seq in bacteria.

The paper demonstrates a synthetic chemoreceptor in E. coli for histamine using computational design and a novel quantitative assay to characterize chemotaxis.