Nicole M. Templeman

This study examines metabolic changes in PCOS-like mice during pregnancy, finding altered glucose homeostasis but no major metabolic dysfunction despite high-fat diet exposure.

The paper shows that lowering insulin levels in mice prevents reproductive aging and diet-induced ovarian dysfunction, linking hyperinsulinemia to subfertility.

This paper shows that CREB regulates reproductive aging in C. elegans by controlling a Hedgehog-related signaling factor, WRT-10, through the TGF-β Sma/Mab pathway in the hypodermis.