Ian W. Campbell

Matched liver and colon RNA-seq timeseries during Citrobacter rodentium infection in mice reveal an intimin-dependent hepatic cytokine burst at 3 days that tracks serum cytokine kinetics.

The paper shows that anoxia activates the CRISPR-Cas system in the mouse intestine via the Fnr regulator, suggesting an adaptation for microbial defense.

InducTn-seq improves transposon mutagenesis by enabling temporal control of transposition, generating diverse mutants and quantifying gene fitness across essential and non-essential genes.

This study shows that reduced motility in Vibrio cholerae decreases inter-animal transmission, while increased motility enhances transmission efficiency in mice.

This paper quantifies Salmonella enterica serovar Typhimurium population dynamics in mice using a barcoded library, revealing bottlenecks, compartmentalization, and dissemination patterns.