Liang Xu

HuR Regulates GATA3-Driven Type 2 Inflammation in CD4⁺ T cells and ILC2 in Airway Inflammation

This study identifies HuR as a regulator of GATA3-driven type 2 inflammation in asthma, showing its inhibition reduces lung inflammation and Th2 cytokine production.

SKiM-GPT: Combining Biomedical Literature-Based Discovery with Large Language Model Hypothesis Evaluation

SKiM-GPT evaluates biomedical hypotheses by combining literature-based discovery with large language models to assess hypothesis validity using retrieved PubMed abstracts.

HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response

This study shows that inhibiting HuR reduces cardiac remodeling after ischemia-reperfusion injury by dampening inflammatory gene expression and immune response, but not initial infarct size.

HuR-dependent expression of Wisp1 is necessary for TGF????-induced cardiac myofibroblast activity

This study shows that HuR-dependent Wisp1 expression is necessary for TGFβ-induced cardiac myofibroblast activity, as HuR inhibition reduces ECM remodeling and contractile functions.