Tania Lintz

Cornichon Homolog-3 (Cnih3) deletion impairs spatial memory, reward-cue association, and fentanyl self-administration behavior.

This study shows that Cnih3 deletion in mice impairs spatial memory, reward-cue association, and fentanyl self-administration, with potential sex-specific effects on opioid use.

Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive behavior

This study shows that peripheral opioid receptor antagonism can reverse fentanyl-induced respiratory depression without causing aversive behaviors.

Prenatal opioid exposure inhibits microglial sculpting of the dopamine system during adolescence

This study shows that prenatal opioid exposure reduces microglial pruning of dopamine D1 receptors in male rats, leading to increased D1R density and impaired extinction of oxycodone-conditioned place preference.

Typical hippocampal transcriptional response across estrous is dysregulated by Cnih3 gene deletion

The paper profiles hippocampal transcriptomes across estrous cycles in mice, identifies estrous-responsive genes, and shows Cnih3 deletion disrupts estrous-specific gene expression patterns.