Author
Boston UniversityORCID 0000-0003-3272-7493Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Laura M. Drepanos, Berta Escude Velasco, Abigail Chase…·John G. Doench
This study compares CRISPR knockout and interference using Perturb-seq, finding consistent transcriptional signatures and tradeoffs in off-target activity and cellular response artifacts.
Kristina M. Fontanez, Yigal Agam, Sophia Bevans…·Robert H. Meltzer
The paper introduces PIPseq V, a single-cell RNA sequencing method using Intrinsic Molecular Identifiers (IMIs) to improve transcript counting and reduce biases compared to traditional UMIs.
Hannah Rickner, Lulu Jiang, Rui Hong…·Christine S. Cheng
The paper develops a 3D neuron-astrocyte coculture model to study tauopathy, showing it recapitulates pathological features and responds to HSP90 inhibitor treatment.