Marshall Scott Padilla

This study develops a fibroblast-derived matrix platform to investigate how tumor-associated EDA-FN-enriched matrices influence macrophage behavior in the tumor microenvironment.

This study resolves heterogeneity in targeted lipid nanoparticles (tLNPs) using biophysical methods, showing that subpopulation structure, not bulk properties, determines targeted RNA delivery.

This paper develops a lipid nanoparticle co-delivering mRNA and a small molecule drug to treat oral cancer by enhancing chemotherapy and reshaping the tumor microenvironment.

This paper presents an automated microfluidic platform for generating large, precisely-defined lipid nanoparticle libraries and evaluates their physicochemical and transfection properties.

This study uses biophysical methods to characterize lipid nanoparticle properties and predict their transfection efficiency.