Author

Christian Haenig

Max Delbrück Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Andranik IvanoviD· 3 shared Erich E. WankeriD· 3 shared Annett Boeddrich· 2 shared Dieter BeuleiD· 2 shared Franziska SchindleriD· 2 shared Leonard Roth· 2 shared Martina Zenkner· 2 shared Nancy Neuendorf· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Andranik IvanovORCID

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Author profile →

3 papers

Recent·Most cited

HAP40 functions as a proteostasis regulator by controlling huntingtin interactions and its release into the extracellular space

Eduardo Silva Ramos, Annett Boeddrich, Christian Haenig, Philipp Trepte, Orchid Ammar, Christopher Secker, Oliver Popp, Andranik Ivanov, Brandon A. Keith, Rachel J. Harding, Franziska Schindler, Tomáš Koudelka, Leonard Roth, Nadine Scharek, Martina Zenkner, , Erich E. Wanker

This study identifies HAP40 as a proteostasis regulator that controls HTT interactions and mHTT secretion, impacting cellular homeostasis and pathobiology.

bioRxiv · Apr 1, 2026 · PreprintCell Biology

Formation of amyloid-like HTTex1 aggregates in neurons, downregulation of synaptic proteins and early mortality of Huntington's disease flies are causally linked

Anne Ast, Leonard Roth, Lydia Brusendorf, Franziska Schindler, Orchid Ammar, Sofie Berberich, Juliane Edel, Megan Bonsor, Elisabeth Georgii, Christian Haenig, Claudia Langnick, Andranik Ivanov, Dieter Beule, Marie Piraud, Séverine Kunz, , Erich E. Wanker

This study links mHTTex1 aggregation in neurons to synaptic dysfunction and early mortality in HD flies through machine learning analysis and RNAi knockdown experiments.

bioRxiv · Feb 6, 2025 · PreprintMolecular Biology

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease

Annett Boeddrich, Christian Haenig, Nancy Neuendorf, Eric Blanc, Andranik Ivanov, Marieluise Kirchner, Philipp Schleumann, Irem Bayraktaroğlu, Matthias Richter, Christine Molenda, Anje Sporbert, Martina Zenkner, Sigrid Schnoegl, Christin Suenkel, Luisa‐Sophie Schneider, , Erich E. Wanker

This study identifies Arl8b as a potential biomarker for Alzheimer's disease by analyzing proteomic changes in 5xFAD mouse brain regions and CSF from AD patients.

Genome Medicine · Jul 19, 2023Peer-reviewedMolecular Biology