Author

Angela Caruso

Istituto Superiore di SanitàORCID 0000-0002-6364-3922Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1

Frequent Co-Authors

Cathy FernandesiD· 2 shared Jacob EllegoodiD· 2 shared Jason P. LerchiD· 2 shared M. Albert BassoniD· 2 shared María Luisa ScattoniiD· 2 shared Alberto GalbuseraiD· 1 shared Alessandro GozziiD· 1 shared Alessio DeloguiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Cathy FernandesORCID

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2 papers

Recent·Most cited

Deficiency of the histone lysine demethylase KDM5B causes autism-like phenotypes via increased NMDAR signalling

Leticia Pérez‐Sisqués, S. Bhatt, Angela Caruso, Mohi U. Ahmed, Talia E. Gileadi, Shoshana Spring, Eleanor Hendy, Joyce Taylor‐Papadimitriou, Diana Cash, Nicholas E. Clifton, Jacob Ellegood, Laura C. Andreae, Jason P. Lerch, María Luisa Scattoni, Karl-Peter Giese, , M. Albert Basson

This study shows that KDM5B deficiency in mice leads to autism-like behaviors and increased brain size, which can be mitigated by NMDAR antagonists.

bioRxiv · May 28, 2024 · PreprintNeuroscience

Altered neocortical gene expression, brain overgrowth and functional over-connectivity in Chd8 haploinsufficient mice

Philipp Suetterlin, Shaun Hurley, Conor Mohan, Kimberley L. H. Riegman, Marco Pagani, Angela Caruso, Jacob Ellegood, Alberto Galbusera, Iván Crespo‐Enríquez, Caterina Michetti, Yohan Yee, Robert A. Ellingford, Olivier Brock, Alessio Delogu, Philippa H. Francis‐West, , M. Albert Basson

This study examines Chd8 haploinsufficient mice, finding brain overgrowth, altered gene expression, and functional connectivity changes linked to autism-like features.

Cerebral Cortex · Feb 27, 2018Peer-reviewedNeuroscience