Jahn Nitschke

This study uses Dictyostelium discoideum to investigate host responses to Mycobacterium marinum infection, identifying Atg9's role in maintaining vacuole integrity and restricting bacterial growth.

This paper introduces a high-throughput phenotypic host-pathogen assay using Dictyostelium discoideum and Mycobacterium marinum to screen anti-infective compounds, demonstrating its ability to differentiate between antibiotics and anti-infectives.

This study identifies trans-δ-viniferins as promising anti-infective scaffolds against Mycobacterium marinum using a Dictyostelium discoideum infection model and natural product derivatives.

The paper characterizes the proteomic composition of Mycobacterium marinum-containing vacuoles in Dictyostelium discoideum at different infection stages and compares them to other mycobacterial compartments.