Author

Astrid Melotti

University of Geneva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:Drosophila· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Frederic BurdetiD· 2 shared Hubert HilbiiD· 2 shared Marco PagniiD· 2 shared Nabil HannaiD· 2 shared Pierre CossoniD· 2 shared Thierry SoldatiiD· 2 shared Alberto J. ArribasiD· 1 shared Amandine Pradier· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Frederic BurdetORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Time-resolved transcriptomic profiling of Dictyostelium discoideum infection with Mycobacterium marinum reveals Atg9-dependent restriction via maintenance of vacuole integrity

Jahn Nitschke, Justine Toinon, Frederic Burdet, Astrid Melotti, Hubert Hilbi, Pierre Cosson, Marco Pagni, Thierry Soldati, Nabil Hanna

This study uses Dictyostelium discoideum to investigate host responses to Mycobacterium marinum infection, identifying Atg9's role in maintaining vacuole integrity and restricting bacterial growth.

bioRxiv · Sep 12, 2026 · PreprintMicrobiology

Ibrutinib modulates CD19 expression and improves efficacy of CD19-CAR T cells in B-cell lymphoma models

Sisi Wang, Alberto J. Arribas, Chiara Tarantelli, Elisa Civanelli, Guangyu Zhou, Pragallabh Purwar, Amandine Pradier, Astrid Melotti, Francesca Guidetti, Yara Hajj Younes, Lodovico Terzi di Bergamo, Luciano Cascione, Sara Napoli, Emanuele Zucca, Elena Sotillo, , Francesco Bertoni

The paper shows ibrutinib increases CD19 expression in B-cell lymphoma models, improving the effectiveness of CD19-CAR T cells.

bioRxiv · May 26, 2026 · PreprintImmunology

Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress

N. Hanna, Frédéric Burdet, Astrid Melotti, Cristina Bosmani, Sébastien Kicka, Hubert Hilbi, Pierre Cosson, Marco Pagni, Thierry Soldati

This study uses time-resolved RNA-seq to analyze D. discoideum gene expression during M. marinum infection, identifying key pathways involved in host response to damage, stress, and metabolic adaptation.

bioRxiv · Mar 27, 2019 · PreprintSystems Biology