Maribel Anguiano

Computational design of a versatile, zero-radius proximity labeling enzyme

This paper designs a new proximity labeling enzyme, FlexID, using computational methods to improve spatial precision and versatility for mapping protein interactions and proteomes.

Acute in vivo proximity labeling for membrane targeted proteomics in neuronal circuits

The paper develops membrane-targeted TurboID variants for in vivo proteomics in neuronal circuits, identifying subcellular proteins and their changes during acute drug exposure.

Rapid, biochemical tagging of cellular activity history in vivo

This paper introduces CaST, a method to biochemically tag cells with elevated Ca2+ in vivo, and demonstrates its use in tagging prefrontal cortex neurons activated by psilocybin in mice.

The circadian clock conveys thermal and photoperiodic cues to modulate EYES ABSENT via the neuropeptide PDF to regulate seasonal physiology

This study shows that PDF signaling negatively modulates EYA levels to regulate seasonal physiology in Drosophila by integrating thermal and photoperiodic cues.

Novel cerebello-amygdala connections provide missing link between cerebellum and limbic system

The paper identifies a novel disynaptic cerebellum-amygdala pathway via the intralaminar thalamus, providing a mechanistic link between the cerebellum and limbic system for emotional processing.