Jody Clements

The paper presents the complete connectome of the Drosophila male central nervous system and compares it to the female connectome, identifying sex-specific and dimorphic neuronal types.

PEELing provides a platform for analyzing spatially-resolved proteomics data with quality assessment, contamination removal, functional annotation, and visualization tools.

A FIB-SEM connectome of the male Drosophila right optic lobe sorts ∼53,000 neurons into 727 types, with neurotransmitter predictions and 577 matched split-GAL4 lines.

HortaCloud provides a cloud-based platform for collaborative whole-brain neuronal reconstruction from light microscopy data, enabling efficient analysis of large datasets without local hardware.

The paper analyzes mitochondria in the Drosophila connectome, showing variations in size, location, and appearance across cell types and brain regions.

NeuronBridge enables rapid morphological matching of neurons across large datasets imaged with different modalities.

Roughly 23 thousand traced neurons and 10 million TBars of the male Drosophila nerve cord, reconstructed from electron microscopy, typed, and queryable in neuPrint down to motor neurons.

The paper identifies sharp cell-type changes at the granular-dysgranular border in the mouse retrosplenial cortex, showing distinct cell-type compositions compared to the neocortex.

The paper provides a searchable image resource of Drosophila GAL4-driver expression patterns at single neuron resolution to improve cell type identification and split-GAL4 combination prediction.

The paper identifies two excitatory neuron subtypes in the claustrum with distinct molecular and circuit properties, revealing a core-shell spatial arrangement that reconciles conflicting views on its extent.

The paper presents a detailed connectome of the adult Drosophila central brain, including new methods for data analysis and biological insights into neural circuit organization.

The paper assesses the power of sequence covariation to detect conserved RNA structure and finds that some previously unconfirmed RNAs may have sufficient covariation signal.

A dense electron-microscopy reconstruction of half the fly central brain, with nearly every cell typed and queryable online, turns months of tracing partners into a database lookup.

neo4j-based graph data model, web explorer and HTTP/Python API for EM connectomes; on an unpublished dataset with 10s of millions of synaptic elements, most queries finish under a second.