Kenneth J. Hayworth

Focal dopaminergic axon swellings in the dorsolateral striatum of Synj1 R259Q mutant mice are clusters of DAT-rich, onion-like plasma membrane invaginations, and the same region shows reduced evoked dopamine release.

The paper presents the complete connectome of the Drosophila male central nervous system and compares it to the female connectome, identifying sex-specific and dimorphic neuronal types.

PATHFINDER improves neuron reconstruction accuracy and efficiency in mouse brain connectome mapping by reducing error rates and manual effort.

A FIB-SEM connectome of the male Drosophila right optic lobe sorts ∼53,000 neurons into 727 types, with neurotransmitter predictions and 577 matched split-GAL4 lines.

Roughly 23 thousand traced neurons and 10 million TBars of the male Drosophila nerve cord, reconstructed from electron microscopy, typed, and queryable in neuPrint down to motor neurons.

The paper introduces methods to prepare Drosophila brains for high-throughput FIB-SEM connectomics, enabling faster and more accurate imaging of neural connections.

The paper presents a detailed connectome of the adult Drosophila central brain, including new methods for data analysis and biological insights into neural circuit organization.

A dense electron-microscopy reconstruction of half the fly central brain, with nearly every cell typed and queryable online, turns months of tracing partners into a database lookup.

This paper introduces enhanced FIB-SEM technology that significantly increases imaging volume and resolution, enabling large-scale connectomics and cell biology studies.

The paper introduces GCIB-SEM, a 3D electron microscopy technique that provides <10 nm isotropic resolution for large volumes, improving z-resolution and compatibility with multibeam SEMs.

The paper proposes a computational model of thalamic relays that support symbolic and sub-symbolic computations through dynamically partitionable auto-associative networks.