Eric A. Klein

Pharmacologically inhibiting beta-adrenergic receptors during chronic stress mitigates reductions in anaerobic, short-chain fatty acid-producing bacteria in the gut.

This study identifies anionic bacterial sphingolipids, specifically ceramide phosphoglycerate, and shows they increase membrane zeta potential and stiffness.

This study presents five high-resolution structures of CpgD, revealing van der Waals interactions mediate its enantiomeric substrate preference for 2-phospho-D-glycerate.

This study identifies sphingolipid transport proteins in Caulobacter crescentus that function similarly to LPS transport proteins, revealing a shared transport mechanism.

The paper identifies CpgD as a phosphoglycerate cytidylyltransferase essential for ceramide diphosphoglycerate synthesis in Caulobacter crescentus.

This study shows that Pseudomonas aeruginosa uses the sphBC genes to metabolize sphingosine, reducing its inhibitory effects on bacterial growth.