Byron Andrews

This study shows that inhibiting METTL3 with STC-15 causes RNA misprocessing, leading to dsRNA formation and activation of innate immunity in cancer cells.

This study identifies a late-stage quality control step in human mitochondrial ribosome large subunit assembly, showing that MRM2 ablation impairs oxidative phosphorylation through defective translation and accumulation of assembly intermediates.

The paper introduces NASE, a database search engine for RNA mass spectrometry data, demonstrating its ability to identify modified RNA sequences in three datasets.

This paper quantifies protein synthesis and degradation rates in mouse models of neurodegeneration and ageing using metabolic labeling and proteomics, revealing distinct dynamics in disease versus aging.