Sangeeta Chawla

The paper uses spatial profiling to analyze cellular marker changes in murine brain metastases, identifying upregulated immune markers and downregulated neuronal markers.

The paper shows Arc protein is specifically expressed in dendrites of layer 2/3 in association cortex during slow-wave sleep in vitro, linked to intrinsically bursting cells in layer 5.

This study identifies daily and 16-hour gene expression rhythms in C. elegans using RNA-seq, revealing both circadian and novel oscillatory patterns.

The paper identifies GEFs and GAPs modulating Rab10 phosphorylation and abundance by LRRK2-G2019S in neurons, showing Crag acts as a GEF and plx as a conventional GAP.

This study investigates the differential roles of Rab10 in LRRK2-G2019S-induced behavioral deficits in Drosophila dopaminergic neurons, finding that Rab10 modulates specific phenotypes but not others.

This paper expresses human tau proteins in specific Drosophila clock circuits and shows how it disrupts sleep and circadian rhythms in different ways.

This study shows JNK signaling enhances antioxidant defenses in neurons, protecting against oxidative stress and synapse damage in both Drosophila and mammalian models.

This study identifies Rab10 as a critical mediator of LRRK2-G2019S-induced neurodegeneration in specific dopaminergic neurons, showing rescue of visual and motor deficits but not sleep dysfunction.