Author

Sean‐Patrick Riechers

Northwestern UniversityORCID 0000-0001-6933-9174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian R. OrszulakiD· 1 shared Aimee J. AylwardiD· 1 shared Benjamin P. Readhead· 1 shared Casey DaltoniD· 1 shared David M. KnipeiD· 1 shared Douglas Taylor GolenbockiD· 1 shared Elaine T. LimiD· 1 shared Fiachra HumphriesiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Adrian R. OrszulakORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Development of a high-throughput, quantitative platform using human cerebral organoids to study virus-induced neuroinflammation in Alzheimer's disease

Meagan N. Olson, Pepper Dawes, Liam F. Murray, Nathaniel Barton, Jonathan Sundstrom, Adrian R. Orszulak, Samantha M. Chigas, Khanh Tran, Aimee J. Aylward, Michele F. Caliandro, Sean‐Patrick Riechers, Khashayar Afshari, Qi Wang, Manuel G. Garber, Fiachra Humphries, , Elaine T. Lim

This study develops a high-throughput platform using human cerebral organoids to screen for compounds that reverse HSV-1-induced neuroinflammation biomarkers associated with Alzheimer's disease.

npj Dementia · Mar 9, 2026Peer-reviewedGenomics

Neurons undergo pathogenic metabolic reprograming in models of familial ALS

Sean‐Patrick Riechers, Jelena Mojsilovic‐Petrovic, Mehraveh Garjani, Valentina Medvedeva, Casey Dalton, Gerald A. Dienel, Robert Gordon Kalb

The paper identifies metabolic reprogramming in neurons of familial ALS models, showing impaired glycolytic flux with maintained citric acid cycle activity and normal ATP levels.

bioRxiv · Aug 20, 2021 · PreprintNeuroscience