Author

Bruno Figadère

Centre National de la Recherche ScientifiqueORCID 0000-0003-4226-8489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Ahmed HaouziD· 1 shared Antonin MarchaisiD· 1 shared Ariel MéchalyiD· 1 shared Benjamin BardiauxiD· 1 shared Birgit GeoergeriD· 1 shared Blandine Séon‐Méniel· 1 shared Catherine BrenneriD· 1 shared Célia Caillet‐SaguyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Ahmed HaouzORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyActa Pharmaceutica Sinica BPeer-reviewedJun 15, 2026

Engineered flavonoid disrupts mitochondrial AIF/CHCHD4 complex for targeted cancer therapy

Hong-Toan Lai, Daniela Dias‐Pedroso, Maria Eugénia Marques Da Costa…·Catherine Brenner

This paper identifies M30-E05, an engineered flavonoid that disrupts the AIF/CHCHD4 mitochondrial complex, reducing cancer cell viability and tumor growth in xenograft models.

1 citation

humanproteomics

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BiochemistryScientific ReportsPeer-reviewedDec 28, 2025

HTRF-based identification of small molecules targeting SARS-CoV-2 E protein interaction with ZO-1 PDZ2

Flavio Alvarez, Florence Larrous, Ariel Méchaly…·Célia Caillet‐Saguy

This paper identifies small molecules that inhibit the SARS-CoV-2 E protein interaction with ZO-1 PDZ2 using X-ray crystallography, HTRF screening, and docking simulations, with one compound showing antiviral activity.

1 citation

humanstructural biology

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