Juliette Wohlschlegel

The paper identifies NEUROD1 as a factor that, when combined with ASCL1, bFGF, and an Activin A inhibitor, can reprogram human RPE into photoreceptor-like cells.

The paper uses multiome sequencing to show EBF1 regulates sensory cell development in the cochlea by setting the prosensory domain boundary and limiting progenitor proliferation.

This study shows that ASCL1 can reprogram adult and infant macaque Müller glia into retinal ganglion cell-like neurons using a modified vector cassette.

The paper identifies a proliferative region in the fetal human retina that continues to generate neurons late in development, similar to the non-mammalian ciliary marginal zone.

This study shows human Muller glia can generate new neurons in adults using proneural transcription factors in 3D cultures.