Author

Georgios N. Hatzopoulos

École Polytechnique Fédérale de LausanneORCID 0000-0003-4382-4459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:multiple species· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Pierre GönczyiD· 2 shared Adrie H. WestphaliD· 1 shared Alex J. VecchioiD· 1 shared Alexander WoglariD· 1 shared Ana Alcaraz‐SernaiD· 1 shared Andrew M. WollacottiD· 1 shared Bernard Laurent SchneideriD· 1 shared Brahm J. YachniniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Pierre GönczyORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 22, 2025

C. elegans SAS-1 ensures centriole integrity and ciliary function, and operates with SSNA-1

Keshav Jha, Alexander Woglar, Coralie Busso…·Pierre Gönczy

This study shows SAS-1 is essential for centriole integrity and ciliary function in C. elegans and interacts with SSNA-1 to maintain these structures.

2 citations

C. elegansexperimental assay

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BioinformaticsbioRxivPreprintSep 30, 2024

✦ In-depth digest

BindCraft: one-shot design of functional protein binders

Martin Pačesa, Lennart Nickel, Christian Schellhaas…·Bruno E. Correia

Hallucinating binders by backpropagating through AlphaFold2 weights gave, across 12 targets, binders in 10-100% of the designs tested per target, mostly at nanomolar affinity.

111 citations

multiple speciesprotein structure

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