William P. Mannherz

The paper functionally analyzes TERC variants to redefine the human telomerase reverse transcription mechanism, revealing eight templating residues and a hyperactive variant that lengthens telomeres.

This paper introduces a method for targeted genomic integration and rearrangement in human cells using CRISPR-targeted dual flap synthesis, enabling DNA sequence assembly without requiring double-stranded DNA donors or cell cycle progression.

This study shows 6-thio-dG inhibits telomerase by forming a non-productive complex, affecting telomere maintenance in cancer cells.

The paper introduces Binary Cellular Analysis to quantify growth and development by modeling cell division and proliferation, providing equations for fetal growth and body part formation.

The paper introduces two new growth processes, UNI-GROWTH and ALLO-GROWTH, and their mathematical equations to model cellular development across species.