Author

Dan Fu Ruan

Tisch Cancer InstituteORCID 0000-0003-4598-0199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Amir HorowitziD· 2 shared A. Demetriou· 1 shared A. Narasimhan· 1 shared A. Rangel· 1 shared A. Tocheva· 1 shared A.M. FarkasiD· 1 shared Alan SotoiD· 1 shared B. D. Hopkins· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Amir HorowitzORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 2, 2024

The HLA-E/NKG2A axis identifies a therapeutic vulnerability in BCG-unresponsive bladder cancer

Bérengère Salomé, Haocheng Yu, Daniel L Ranti…·Amir Horowitz

This study identifies the HLA-E/NKG2A axis as a therapeutic target in BCG-unresponsive bladder cancer by showing its role in immune evasion and impaired effector cell function.

5 citations

humanbulk RNA-seq

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BioinformaticsPLoS Computational BiologyPeer-reviewedJul 6, 2021

MiDAS - Meaningful Immunogenetic Data at Scale

Maciej Migdał, Dan Fu Ruan, William F. Forrest…·Christian Hammer

MiDAS is an R package that enables statistical analysis of immunogenetic data, including HLA fine mapping, evolutionary divergence, and HLA-KIR interactions.

31 citations

humanstatistical model

𝕏 PostBluesky