Author

Mark Wade

Harvard UniversityORCID 0000-0003-4643-8465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alissa WesterlundiD· 1 shared Andrew P. BarbouriD· 1 shared Anna TrigosiD· 1 shared Charles A. NelsoniD· 1 shared Cuong Phu Duong· 1 shared David S Liu· 1 shared Ebtihal H MustafaiD· 1 shared Eric P. KusnadiiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alissa WesterlundORCID

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2 papers

Recent·Most cited

SMAD4 loss drives chromosomal instability during tumourigenesis via translational reprogramming

Julia V. Milne, Kameng Wu, Eric P. Kusnadi, Sandra Brosda, Kenji Mark Fujihara, Ebtihal H Mustafa, Sasha Witts, Katherine Papastratos, Maree Pechlivanis, Anna Trigos, Metta K. Jana, Paul J. McMillan, Thomas Daniel Jackson, Niko Thio, Yuzhou Feng, , Nicholas James Clemons

This study shows SMAD4 loss reprograms translation to induce chromosomal instability, driving tumourigenesis, and identifies CDK11B-p58 as a key mediator.

bioRxiv · Mar 25, 2026 · PreprintCancer Biology

Child Growth Predicts Brain Functional Connectivity and Future Cognitive Outcomes in Urban Bangladeshi Children Exposed to Early Adversities

Wanze Xie, Sarah K. G. Jensen, Mark Wade, Swapna Kumar, Alissa Westerlund, Shahria Hafiz Kakon, Rashidul Haque, William A. Petri, Charles A. Nelson

The paper examines how child growth affects brain functional connectivity and future cognitive outcomes in Bangladeshi children exposed to early adversity, finding that faltered growth is linked to altered connectivity and reduced IQ.

BMC Medicine · Nov 24, 2019Peer-reviewedNeuroscience