David S. Gilmour

This study isolates and structures native Pol II transcription complexes and nucleosomes from Drosophila embryos, revealing new insights into transcription dynamics and nucleosome interactions.

The paper shows that Integrator complex depletion disrupts histone gene expression timing by dispersing transcription machinery clusters.

The paper shows that a truncated CTD with only YSPTSPS repeats supports Drosophila viability, while longer CTDs with more repeats are defective and localize to nuclear foci.