Author
University of St AndrewsORCID 0000-0003-4692-2222Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Emma Hobbs, T.M. Gloster, Leighton Pritchard
The paper catalogs and analyzes CAZyme complements in Pectobacterium and Dickeya genomes, finding coevolution of CAZymes linked to host adaptation and tissue preference.
Haotian Chi, Ville Hoikkala, Stephen A. McMahon…·Malcolm F. White
This study describes the structure and mechanism of Crn4, a ring nuclease that degrades cyclic oligoadenylates and modulates type III CRISPR immunity.
Marta Orzechowski, Ville Hoikkala, Haotian Chi…·Malcolm F. White
The paper shows that a viral SAVED domain, AcrIII-2, degrades the CRISPR second messenger cA4, inhibiting its effectors.
Haotian Chi, Stephen McMahon, Lukas Daniel-Pedersen…·Malcolm F. White
This study investigates the structure and function of a SAM-AMP lyase from Clostridium botulinum, showing its ability to substitute for a phosphodiesterase in providing anti-phage defence.
Emma Hobbs, T.M. Gloster, Leighton Pritchard
cazy_webscraper compiles and integrates CAZyme data from CAZy and other sources, enabling large-scale bioinformatic analysis and candidate screening for biotechnological applications.