Frank Jülicher

This study investigates how protein droplet capillary forces regulate clathrin-mediated endocytosis by stalling and then driving membrane invagination.

The paper shows that confined actomyosin networks generate self-centering steady-state flows that organize cellular debris into a central inclusion.

This study shows that FUS protein fibers grow in the dilute phase around condensates, which transition to a glassy state, revealing two coexisting solid-like phases in protein condensation.

The paper identifies injury-induced electrochemical coupling between tissue depolarization and intracellular signaling as essential for organ regeneration in zebrafish.

This study investigates how the apical extracellular matrix (aECM) regulates fold morphogenesis in the Drosophila wing disc, showing its role in stabilizing tissue folding and shaping the adult wing.

The paper identifies an active torque dipole in avian embryos that drives left-right symmetry breaking through tissue rotation.

The paper shows a protein-DNA co-condensate forms a surface hydrogel that mechanically reinforces the nucleus and protects DNA from damage during mechanical stress.

This study investigates how DNA loop extrusion interacts with protein-DNA condensation, showing that loop extrusion enhances condensation dynamics and leads to domain formation similar to TADs.

This paper shows that concentration buffering and noise reduction in phase separating systems are distinct concepts, neither of which is required or sufficient for the other.

The paper derives a model for molecular transport across phase boundaries in coexisting liquid phases and identifies two physical scenarios that lead to an effective transport resistance.

The paper shows that cortical pulling forces misalign the mitotic spindle with the cell's long axis, but an actomyosin-based cell rotation corrects this, aligning the spindle with the long axis, thus fulfilling Hertwig's rule.

The paper shows active cellular behaviors drive 3D shape changes in Drosophila wing disc pouch through spontaneous strains, validated by MyoVI knockdown.

The paper investigates the role of core PCP mutations in Drosophila pupal wing morphogenesis and finds they do not affect tissue shape changes but influence fast mechanical responses.

The paper shows that hydraulic instability in C. elegans germ cells leads to cell death by causing volume differences and extrusion of shrinking cells.

The paper investigates how tissue-scale patterns of cell shape and mechanical stress emerge in Drosophila wing imaginal discs through self-organized mechanosensitive feedback.

The paper shows that p120-Catenin's mechanosensitive binding regulates E-Cadherin turnover and epithelial viscoelasticity in Drosophila pupal wings.

The paper quantifies how cell divisions and rearrangements drive anisotropic growth in Drosophila wing discs under 20E treatment.