Saikat Mukhopadhyay

This study identifies ANKMY2's role in ciliary adenylyl cyclase trafficking, showing its suppression reduces cystogenesis in ADPKD models without affecting cAMP levels or cilia structure.

The paper identifies Gs pathway inactivation as an SMO-independent Hedgehog signaling driver in BCC and shows adenosine 2B receptor activation can counteract SMO-driven oncogenesis.

The paper identifies a programmed cilia deconstruction pathway in cerebellar granule cells during neurogenesis, showing decreased cilia maintenance and centriole capping prevent cilia regrowth and dysregulated signaling.

This study investigates the spatiotemporal dynamics of primary and motile cilia during lung development, revealing distinct patterns in endothelial, epithelial, and mesenchymal cells.

The paper investigates ciliary dynamics in differentiating granule cell neurons, finding that cilia are deconstructed intracellularly and do not reform in adult neurons.

This study shows that ciliary and extraciliary Gpr161 pools repress hedgehog signaling differently in various tissues, affecting developmental outcomes.