Author

Nell Saunders

Institut PasteurORCID 0000-0002-0872-1529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Olivier SchwartziD· 2 shared Amelie WileveauiD· 1 shared Arnaud L FontanetiD· 1 shared Catherine BlanciD· 1 shared Chloé Petiot· 1 shared Darragh DuffyiD· 1 shared Delphine PlanasiD· 1 shared Elodie Le Seac’h· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCell Biology

Olivier SchwartzORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

SARS-CoV-2 ORF9b exploits mitochondrial recruitment to TOMM70 for proteasomal protection and tunes inflammatory remodeling during lung infection

Yining Zhao, Lauriane Kergoat, Guilherme Dias de Melo, Florence Larrous, Guillaume Drumont, Juan Diego Hernández‐Camacho, Elodie Vimont, Elodie Le Seac’h, Nell Saunders, Martin Kächele, Étienne Kornobis, Quentin Giai Gianetto, Mariette Matondo, Isabelle Tardieux, Olivier Schwartz, , Timothy Wai

This study shows SARS-CoV-2 ORF9b uses TOMM70 to avoid proteasomal degradation, reduces inflammation, and is not essential for viral replication or lung pathology.

bioRxiv · Aug 3, 2026 · PreprintCell Biology

Temperature-Dependent Replication and Sensitivity to Innate Immunity of Human Coronavirus HKU1

Julian Buchrieser, Eva Thuillier, Jeanne Postal, Amelie Wileveau, Florence Guivel‐Benhassine, Isabelle Staropoli, Nell Saunders, Delphine Planas, Jamie A. Sugrue, Vincent Bondet, Ignacio Fernández, François Bontems, Françoise Porrot, Chloé Petiot, Matthieu Prot, , Olivier Schwartz

This study shows human coronavirus HKU1 replicates more efficiently at nasal temperature (33°C) than at body temperature (37°C), with differences in innate immune response and viral stability.

Nature Communications · Jul 27, 2026Peer-reviewedMicrobiology