Author

Ignacio Fernández

Centre National de la Recherche Scientifique

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Ahmed HaouziD· 1 shared Atousa Arbabian· 1 shared Catherine BlanciD· 1 shared Eduard BaqueroiD· 1 shared Felix Augusto ReyiD· 1 shared Julian BuchrieseriD· 1 shared Nell SaundersiD· 1 shared Olivier SchwartziD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ahmed HaouzORCID

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1 paper

Recent·Most cited

Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus

Ignacio Fernández, Nell Saunders, S. Duquerroy, William Bolland, Atousa Arbabian, Eduard Baquero, Catherine Blanc, Pierre J. Lafaye, Ahmed Haouz, Julian Buchrieser, Olivier Schwartz, Felix Augusto Rey

This study determines the structure of HKU1-CoV receptor binding domain in complex with TMPRSS2, identifying key residues for host tropism and revealing the structural basis of TMPRSS2 activation.

Cell · Jul 3, 2024Peer-reviewedBiochemistry