Sabrina Absalon

This study identifies PfAP2-HCR as a critical transcription factor regulating host cell remodeling in Plasmodium falciparum, essential for parasite survival and transmission.

This study identifies essential enzymes in the pyrimidine biosynthesis pathway of Plasmodium falciparum and demonstrates their critical roles in parasite survival.

This study identifies PfCoronin's role in artemisinin resistance by showing mutations impair hemoglobin uptake and modulate drug susceptibility during the ring stage of Plasmodium falciparum.

The paper uses cryo-ET to show IFT trains dock at specific MTD positions in trypanosome flagella, revealing spatial regulation independent of IFT-B structure.

This paper identifies PfAnchor as an essential protein for apicoplast fission and inheritance in Plasmodium falciparum, showing its interaction with PfDyn2 and its role in parasite survival.

This study uses high-resolution proteomics to show that Plasmodium infection disrupts mosquito salivary glands, causing exchange of proteins between hemolymph and saliva.

This study uses expansion microscopy to investigate sporozoite biology in malaria parasites, revealing new insights into rhoptry function and identifying a key protein involved in invasion.

The paper uses ID-oPD to map spinophilin's interactome, identifying proteins involved in mRNA processing and translation, and suggests a role in synaptic protein expression.

This study identifies the global release of translational repression in Plasmodium parasites during host-to-vector transmission using transcriptomics and proteomics.

This study uses U-ExM and RITE to show Nup221 turnover in P. berghei NPCs during blood-stage replication.

The paper introduces MoTissU-ExM, a method to expand mosquito tissues for visualizing malaria parasites, enabling ultrastructural analysis of both host and parasite structures.

This study shows that RON11 is essential for the biogenesis of the second rhoptry in Plasmodium falciparum merozoites and is required for erythrocyte invasion.