Matteo Carandini

This study shows that functional ultrasound signals correlate with neural firing rates in awake mice, revealing a direct relationship between hemodynamic signals and neuronal activity.

This study identifies causal roles of visual and frontal cortex in a visual decision task using optogenetic inactivation and neural recordings.

The paper investigates how dopamine axons in different striatal regions encode sensory stimuli and actions during decision-making tasks in mice.

The paper shows that training on a visuomotor task alters visual cortical population codes by orthogonalizing responses to motor-associated stimuli, without improving optimal decoders but enhancing suboptimal ones.

This paper develops a standardized task for measuring decision-making in mice, showing reproducible results across multiple laboratories and providing a public dataset and tools.

The paper shows that mouse frontal cortex combines auditory and visual evidence additively during learning, mirroring behavior, and that this combination is impaired by optogenetic inactivation.

The paper introduces Neuropixels 2.0, a high-density probe for long-term brain recordings, and demonstrates its stability across months in multiple labs and species.

The paper shows spatial modulation of visual signals in higher visual areas but not in the thalamic pathway to V1, and links this modulation to active navigation and experience.

The paper shows that striatal activity patterns mirror cortical activity patterns, with an additive offset in learned tasks.

This study investigates cortical state fluctuations during sensory decision making and finds that desynchronization correlates with task engagement rather than accuracy.

This study shows that spatial representations in V1 and CA1 are correlated and influenced by non-visual factors like distance traveled and theta oscillations.

The paper shows that mean-field models of cortical dynamics require inclusion of thalamic interactions to accurately predict responses to optogenetic stimulation in awake mice.

Rigbox is an open-source software toolbox for behavioral neuroscience experiments, offering modular design, hardware I/O, data synchronization, and stimulus presentation.

The paper shows that retinal outputs in mice are modulated by behavioural state, as observed in the superficial superior colliculus and optic tract, even in darkness.

The paper records neuronal activity across the mouse brain during a visual task and finds widespread activation and specific midbrain circuits involved in choice.

The paper analyzes the correlation structure of natural image coding in visual cortical populations of awake mice, finding a power-law decay in principal component variance that reflects coding smoothness.

This study shows that bilateral ongoing activity in mouse cortex explains much of the variability in sensory responses during a visual detection task.

The paper shows that spontaneous brain activity encodes multidimensional behavioral information across the forebrain, alongside sensory input in orthogonal dimensions.

This study investigates how mice integrate sensory confidence and reward value in decision-making and learning, revealing distinct roles for frontal and dopamine neurons.

This study identifies the functional organization of excitatory and inhibitory intracortical circuits in mouse V1 that contribute to orientation and direction selectivity.

This study investigates PPC neuron activity during virtual navigation in mice, finding that spatial position and heading angle predict neural activity better than decision or other variables.

MATLAB tool registers histology slices to the Allen Mouse Brain Atlas and traces electrode tracks across them, reported to localize recording sites more accurately than eyeballing the atlas.

The paper shows that visual responses in V1 and hippocampal CA1 encode the animal's subjective spatial position during navigation in virtual reality.

The paper examines how locomotion affects neuron interactions in mouse visual cortex, finding that it alters synaptic connectivity rather than just disinhibition.

This paper introduces high-yield methods for two-alternative visual psychophysics in head-fixed mice, showing rapid learning and accurate psychometric curves.

The paper reports aberrant cortical activity and fluorescence events in some GCaMP6-expressing transgenic mice, suggesting potential artifacts in neuronal recordings.

This study shows that focal seizures in mice start as standing waves in V1 and propagate following homotopic connectivity patterns similar to normal visual processing.

Suite2p processes two-photon calcium movies faster than real time on desktop workstations, roughly doubling curated cell yield over CNMF and recovering 13,451 neurons in one session.

The paper identifies the source and modulation factors of a narrowband gamma oscillation in mouse visual cortex, showing it is driven by thalamic input and suppressed by visual contrast.

This study shows that immobile silicon probes can provide stable, long-term neuronal recordings in mice for several months without microdrives.