Pierre A. Neveu

This study shows that mouse brain lipotypes develop in two stages, with cholesterol increasing postnatally, and that stem cell-derived neurons do not fully recapitulate this lipotype.

The paper shows RNA regulates ENO1 enzyme activity, affecting glycolysis and stem cell differentiation in human and mouse cells.

This study identifies two RA pathway mechanisms controlling neural progenitor formation in a PS-like context using mESCs and single-cell RNA sequencing.

The paper systematically quantifies microRNA affinities in vivo using mouse embryonic stem cells and finds that miRNA target affinities vary widely and correlate with expression levels.

This study uses optogenetic inhibition of Delta in Drosophila to show that Notch signaling exhibits digital behavior during tissue differentiation, with duration determining tissue-level responses and switch-like mechanisms at the cellular level.