Svenja Lenhard

This study shows that mitochondrial presequences function in cytosolic quality control and trigger a heat shock response when mitochondrial import is inhibited.

This study shows that aneuploidy disrupts proteostasis, leading to mitochondrial dysfunction and accumulation of mitochondrial precursor proteins in cytosolic p62 bodies.

The paper shows that eukaryotic Prx1/AhpC-type peroxiredoxins form heterooligomers, which modulate their structure and stability, challenging the previous belief in homooligomerization.