Author

Shichen Zhang

Johns Hopkins UniversityORCID 0009-0001-0618-2736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:electronic health records· 1 Approach:statistical model· 1

Frequent Co-Authors

Elissa SutliefiD· 1 shared Haohong LiiD· 1 shared Heping ChengiD· 1 shared Jianzhi ZengiD· 1 shared Jing ZouiD· 1 shared Kate Forsberg· 1 shared Ke TaniD· 1 shared Liangyi CheniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Elissa SutliefORCID

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2 papers

Recent·Most cited

Accumulation of neural state transitions in dorsomedial striatum predicts patch foraging decisions

Elissa Sutlief, Shichen Zhang, Kate Forsberg, Marshall G. Hussain Shuler

The paper identifies a time-cost-variable accumulation-to-threshold computation in the dorsomedial striatum that predicts when mice exit foraging patches based on reward history and environmental context.

bioRxiv · Sep 29, 2025 · PreprintNeuroscience

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

Miao Jing, Yuexuan Li, Jianzhi Zeng, Pengcheng Huang, Miguel Skirzewski, Ornela Kljakic, Wanling Peng, Tongrui Qian, Ke Tan, Jing Zou, Simon Trinh, Runlong Wu, Shichen Zhang, Sunlei Pan, Samuel Andrew Hires, , Yulong Li

The paper develops an optimized GRABACh sensor to measure in vivo cholinergic activity in Drosophila and mice, revealing compartmental ACh signals and single-trial dynamics.

Nature Methods · Sep 28, 2020Peer-reviewedNeuroscience