Author

Katsiaryna Maskalenka

Babraham InstituteORCID 0009-0001-0809-0704Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Adam BendalliD· 2 shared Adam Pickles· 1 shared Alexander E. EpsteiniD· 1 shared Aliaksandra RadzisheuskayaiD· 1 shared Amanda Andersson-RolfiD· 1 shared Andreas Welsh· 1 shared Asif NakhudaiD· 1 shared Aylwyn ScallyiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Adam BendallORCID

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3 papers

Recent·Most cited

A single factor for safer cellular rejuvenation

Lucas Paulo de Lima Camillo, Rihab Gam, Katsiaryna Maskalenka, Francis Leblanc, Gustavo Antonio Urrutia, Gabriel Mejia, Henry E. Miller, Christopher P. Wardlaw, Adam Pickles, Laura Everton, Ringaile Zaksauskaite, Rejina B. Khan, Andreas Welsh, Samira Gambo, Stephany Gallardo, , Brendan Swain

This paper identifies SB000, a single gene factor that rejuvenates cells from multiple germ layers without inducing pluripotency, rivaling the effectiveness of Yamanaka factors.

bioRxiv · Jun 5, 2025 · PreprintCell Biology

NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naive pluripotent stem cells

Katsiaryna Maskalenka, Gökberk Alagöz, Felix Krueger, Joshua Wright, Maria Rostovskaya, Asif Nakhuda, Adam Bendall, Christel Krueger, Simon A. Walker, Aylwyn Scally, Peter J. Rugg‐Gunn

The paper shows NANOGP1, a duplicate of NANOG, has partial functional conservation in human naive pluripotent stem cells, contributing to pluripotency but not maintaining undifferentiated status.

Development · Jan 9, 2023Peer-reviewedDevelopmental Biology

Sox2 modulation increases naive pluripotency plasticity

Kathryn Tremble, Giuliano Giuseppe Stirparo, Lawrence E. Bates, Katsiaryna Maskalenka, Hannah T. Stuart, Kenneth Jones, Amanda Andersson-Rolf, Aliaksandra Radzisheuskaya, Bon‐Kyoung Koo, Paul Bertone, José Silva

This study shows that low Sox2 expression in naive pluripotent stem cells enhances their developmental plasticity without impairing neuroectoderm differentiation.

iScience · Feb 7, 2021Peer-reviewedDevelopmental Biology