Tyler Roy

This study identifies a shared genetic regulator linking metabolism and addiction-related behavior in mice and humans through a common enhancer regulating Eed/Me3 and EED/ME3.

The paper examines behavioral variation in cocaine self-administration across multiple phases in genetically diverse mouse populations, identifying strain and sex differences and extreme strains for drug intake traits.

This study identifies and validates 22 genes that drive drug intake and related behavioral traits in mice through knockout screening and behavioral assays.

The paper identifies genetic factors influencing opioid-induced respiratory depression in mice using genetic mapping and functional analysis.

This study shows that including genetic and sex differences in mice improves the alignment of addiction-related traits with human studies.