Author

Ying Xu

Howard Hughes Medical InstituteORCID 0009-0002-8618-1561Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ying Xu6 papers · Changchun University of Technology

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jason G. CysteriD· 3 shared Jinping AniD· 3 shared Konrad KnöpperiD· 2 shared Aashish ManglikiD· 1 shared Ananya KrishnapuraiD· 1 shared Anshul RaoiD· 1 shared Arushi Singhal· 1 shared Christian B. BillesbølleiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

Jason G. CysterORCID

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3 papers

Recent·Most cited

Sex hormones gate the neuronal control of dendritic cell migration and immunity

Konrad Knöpper, Tamar L. Ben-Shaanan, Jinping An, Ying Xu, Jason G. Cyster

The paper shows sex hormones influence how immune cells respond to neuronal signals, affecting immune responses in males and females.

bioRxiv · Oct 6, 2026 · PreprintImmunology

GPCR-Ga13 signaling regulates survival of intestinal intraepithelialCD8 lymphocytes through migration to cytokine-rich niches

Zachary M. Earley, Anshul Rao, Longhui Qiu, Konrad Knöpper, Fanglue Peng, Norihide Jo, Ananya Krishnapura, Wioletta Lisicka, Hanna Taglinao, Jinping An, Ying Xu, Li V. Yang, Dan Liu, Mark R. Looney, Jason G. Cyster

This study shows that GPCR-Ga13 signaling is essential for intestinal IEL survival by enabling migration to cytokine-rich niches, with loss of G13 leading to impaired function and increased disease severity.

bioRxiv · Aug 3, 2026Immunology

Phenotypic pleiotropy of missense variants in human B cell-confinement receptor P2RY8

Taylor N. LaFlam, Christian B. Billesbølle, Tuan Dinh, Finn D. Wolfreys, Erick Lu, Tomas Matteson, Jinping An, Ying Xu, Arushi Singhal, Nadav Brandes, Vasilis Ntranos, Aashish Manglik, Jason G. Cyster, Chun Ye

The paper uses deep mutational scanning and structural analysis to study the functional effects of missense variants in the P2RY8 receptor and improves variant effect predictions.

Cell Genomics · Sep 11, 2025Peer-reviewedGenomics