Author
Howard Hughes Medical InstituteORCID 0000-0002-4735-9745Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Konrad Knöpper, Tamar L. Ben-Shaanan, Jinping An, Ying Xu, Jason G. Cyster
The paper shows sex hormones influence how immune cells respond to neuronal signals, affecting immune responses in males and females.
bioRxiv · Oct 6, 2026 · PreprintImmunology
Zachary M. Earley, Anshul Rao, Longhui Qiu, Konrad Knöpper, Fanglue Peng, Norihide Jo, Ananya Krishnapura, Wioletta Lisicka, Hanna Taglinao, Jinping An, Ying Xu, Li V. Yang, Dan Liu, Mark R. Looney, Jason G. Cyster
This study shows that GPCR-Ga13 signaling is essential for intestinal IEL survival by enabling migration to cytokine-rich niches, with loss of G13 leading to impaired function and increased disease severity.
bioRxiv · Aug 3, 2026Immunology
Raphaël Mattiuz, Jesse Boumelha, Emmanouil Aerakis, Jessica Le Bérichel, Pauline Hamon, László Halász, Abishek Balachandra Vaidya, Brian Y. Soong, Emir Radkevich, Hye Mi Kim, Matthew D. Park, Romain Donné, Leanna Troncoso, Rachel A. Kaplan, Clotilde Hennequin, , Miriam Mérad
This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.
Science · Jul 16, 2026Peer-reviewedImmunology
Konrad Knöpper, Anshul Rao, Jinping An, Jason G. Cyster
This study identifies ABCC1's role in protecting skin dendritic cells from FITC toxicity through intracellular efflux and extracellular glutathione buffering.
Proceedings of the National Academy of Sciences · Mar 5, 2026Peer-reviewedImmunology
Qi Liu, Peixin Amy Chen, Esha Urs, Shimin Zhang, Maya M. Arce, Charlotte H. Wang, Zhongmei Li, Jin Seo, Nupura Kale, Taylor N. LaFlam, Fanglue Peng, Eric Shifrut, Greg M. Allen, Justin Eyquem, Katherine Cynthia Fuh, , Julia C. Carnevale
This paper performs in vivo CRISPR screens in human T cells to identify genetic modifiers of T cell function in solid tumors, finding P2RY8-G13 and GNAS as key regulators.
bioRxiv · Sep 23, 2025 · PreprintImmunology
Taylor N. LaFlam, Christian B. Billesbølle, Tuan Dinh, Finn D. Wolfreys, Erick Lu, Tomas Matteson, Jinping An, Ying Xu, Arushi Singhal, Nadav Brandes, Vasilis Ntranos, Aashish Manglik, Jason G. Cyster, Chun Ye
The paper uses deep mutational scanning and structural analysis to study the functional effects of missense variants in the P2RY8 receptor and improves variant effect predictions.
Cell Genomics · Sep 11, 2025Peer-reviewedGenomics
Simon J. Cleary, Longhui Qiu, Yurim Seo, Peter Bałuk, Dan Liu, Nina Kathrin Serwas, Catherine A. Taylor, Dongliang Zhang, Jason G. Cyster, Donald M. McDonald, Matthew F. Krummel, Mark R. Looney
This paper develops a technique for intravital imaging of pulmonary lymphatics in mice, revealing ventilation-dependent and -independent lymph flow and leukocyte migration during inflammation and cancer metastasis.
The Journal of Experimental Medicine · Feb 19, 2025Peer-reviewedImmunology
Elizabeth Theusch, Flora Ting, Yuanyuan Qin, Kristen Stevens, Devesh Naidoo, Sarah M. King, Neil Victor Yang, Joseph Orr, Yuyuan Han, Jason G. Cyster, Yii‐Der Ida Chen, Jerome I. Rotter, Ronald M. Krauss, Marisa Wong Medina
The paper identifies ZNF335 as a gene modulating statin response by analyzing cell line transcriptomics and mouse models.
Genome Medicine · Jul 26, 2024Peer-reviewedGenomics