Author

Maitriyee Mahanta

ORCID 0009-0002-8920-4159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Aditi DeshpandeiD· 1 shared Alexander N.R. WeberiD· 1 shared Assem DuisembekovaiD· 1 shared Barry A. MorganiD· 1 shared Bénédicte F. PyiD· 1 shared Chloe M. McKeeiD· 1 shared CLAUDIA PORTILLOiD· 1 shared Dominic FerberiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Aditi DeshpandeORCID

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1 paper

Recent·Most cited

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah U. Tronnes, Maitriyee Mahanta, MATTHEW BANICKI, MARY COCHRAN, Samantha Cowdin, Kristen Fortney, George D. Hartman, Robert E. Hughes, Rusty L. Montgomery, CLAUDIA PORTILLO, Paul D. Rubin, Taiz Salazar, Yan Wang, , Rebecca C. Coll

This paper characterizes BAL-0028, a novel NLRP3 inhibitor with a distinct binding site and mechanism, showing potent inhibition of human and primate NLRP3 and efficacy in a peritonitis model.

The Journal of Experimental Medicine · Jul 24, 2025Peer-reviewedImmunology