Erica Keane Rivera

This study identifies small-molecule inhibitors of the tau-LRP1 interaction using biochemical assays and high-throughput screening, showing reduced tau uptake in cellular assays.

This study identifies how APOE3-Christchurch astrocytes protect against Alzheimer's by enhancing tau clearance and reducing harmful lipids.

This paper develops a protein-like polymer that inhibits tau fibril propagation in human-derived models of neurodegeneration by targeting a specific structural motif of 4R tau isoforms.

The paper designs a 19-residue peptide that selectively induces aggregation of 4R tau over 3R tau, revealing structural and amino acid determinants of tauopathy propagation.